The study design was approved by the Ethics Committee of Yuzuncu Yil University. In this study, we aimed to investigate the diagnostic value of MPV in acute appendicitis at childhood.Ĭurrent study was carried out with 100 patients diagnosed as acute appendicitis chosen retrospectively among patients admitted to the Pediatrics and Pediatric surgery clinics of Diyarbakir Children's Hospital between 20, and 100 healthy individuals. There are available studies performed on adults available indicating that MPV values may be a valuable method in the diagnosis of acute appendicitis 11. Platelet volume is known to be a marker determined from megakaryocytes during platelet production, which is associated with platelet function and activation 6 – 10. The mean platelet volume (MPV) is a parameter detected during routine blood count and to which clinicians do not usually pay attention. However, the results of these studies have been found distinct and conflicting 3. Thus, many studies investigating the diagnostic value of laboratory inflammatory markers have been carried out in recent years. New markers are needed that would decrease the rate of negative laparatomies in cases with the prediagnosis of AA and that would not lead to a delay in the diagnosis, that would be easily applicable everywhere, be cheap, non-invasive, and that would not cause a loss in time. Thus, determining new methods to distinguish non-specific abdominal pain from AA and decreasing the rate of negative laparatomy is still required. Imaging methods such as ultrasonography and computerized tomography are promising for the early and accurate diagnosis, however, they are not sufficient 4 – 5. Unfortunately, clinical history, physical examination and routine laboratory tests do not provide sufficient data to confirm the diagnosis of AA in the early period. Furthermore, negative exploration rates still are 20–30% 1 – 3.
Delay in the diagnosis of AA leads to an increase in the risk of severe and advanced complications such as perforation. The clinical diagnosis of acute appendicitis (AA) in children is still problematic.
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